Do you have a bullet preference in the .257 WM for an "all around game" bullet?
I have used the 100 TTSX for quite a while but I am curious about the 110 Accubond. Salvaging as much meat as possible is important to me.
The 110 grain accubond is a bomb even at .257 Roberts velocity. I shot 2 deer with it one day. Both broadside or perhaps angling with their heads slightly forward, no heavy bone, nothing but ribs. Both bullets grenaded inside. There were tiny fragment holes through the .. not sure what you call it, but the sort of lining to the chest cavity .. on the off side but enough mass hitting there to completely jello .. and I mean purple soup pouring out when I quartered them .. the off side shoulder. Of the two deer, 3 of 4 front shoulders and the front half of 3 of 4 backstraps weren't even fit for a buzzard to eat.
So at .257 Weatherby velocity .. might be a good coyote bullet if you don't want the hide but that's it.
I'd go monolithic of some sort if you want to minimize meat damage and if possible, download slightly. Not all guns shoot the monolithic bullets well, certainly not well enough to need .257 weatherby velocity, but if none of them work, I'd consider the 120 grain partition or even 115 grain ballistic tip before I shoot any more animals with the 110 grain accubond.