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I would think that something a little faster than R-17 would be best in the 416 Ruger, for the following reasons.
Our 416Rigby's like 101.5 grains of R-17 with the 350 grain TTSX for 2825 fps. Since the Rigby case is cavernous in comparison, and since straighter-walled cartridges tend to prefer faster powders, the 416 Ruger should probably prefer something a little faster than R-17. Of course, R-17 might produce just what you are looking for in the 416 Ruger. But R-15 might add just a tad of fps and capacity balance.
